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Petricevic, L; Kaufmann, U; Domig, KJ; Kraler, M; Marschalek, J; Kneifel, W; Kiss, H; .
(2014): Rectal Lactobacillus Species and Their Influence on the Vaginal Microflora: A Model of Male-to-Female Transsexual Women.
J Sex Med. 2014; 11(11):2738-2743 FullText FullText_BOKU

Abstract:
IntroductionBased on Lactobacillus species co-colonizing the vagina and rectum, it has been hypothesized that the rectum may be an important reservoir for vaginal colonization by lactobacilli. There are no data on this issue in male-to-female transsexual women. AimWe undertook this observational study to characterize the Lactobacillus species present in the neovagina and rectum of male-to-female transsexual women and to determine the degree of neovaginal-rectal co-colonization in order to gain a better understanding of the potential role of the gut as a reservoir for genital lactobacilli. MethodsSixty-one male-to-female transsexual women with penile skin lined neovagina without clinical signs of infection were recruited on an ongoing basis from among male-to-female transsexual outpatients. Neovaginal and rectal smears were taken for molecular Lactobacillus species profiling by denaturing gradient gel electrophoresis (PCR-DGGE). Main Outcome MeasuresMatching Lactobacillus species between neovagina and rectum. ResultsForty-three of the 61 male-to-female transsexual women (70.5%) simultaneously harbored the same lactobacilli in both the neovagina and rectum. We found 276 neovaginal and 258 rectal DGGE bands representing 11 Lactobacillus species, with 201 matches of the same Lactobacillus species in neovagina and rectum. 37 of the 61 women (61%) had two or more matching Lactobacillus species. ConclusionThese data support the hypothesis that the rectum may play an important role as source of Lactobacillus species that colonies neovagina of male-to-female transsexual women. In view of the specific anatomical circumstances of the study population, these findings may be extended to the general population of women. Petricevic L, Kaufmann U, Domig KJ, Kraler M, Marschalek J, Kneifel W, and Kiss H. Rectal Lactobacillus species and their influence on the vaginal microflora: A model of male-to-female transsexual women. J Sex Med 2014;11:2738-2743.
Authors BOKU Wien:
Domig Konrad
Kneifel Wolfgang
Kraler Manuel
BOKU Gendermonitor:


Find related publications in this database (Keywords)
Lactobacillus
Vaginal Lactobacilli
Neovagina
Rectum
Transsexual Women
Gender Dysphoria


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