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Selected Publication:

van den Oever, SP; Mayer, HK.
(2022): Biologically active or just "pseudo"-vitamin B-12 as predominant form in algae-based nutritional supplements?
J FOOD COMPOS ANAL. 2022; 109, 104464 FullText FullText_BOKU

In order to find out whether algae-based nutritional supplements contain both physiologically active vitamin B-12 and its non-active pseudo-form, a simple and fast ultra-high performance liquid chromatography method with UV detection was developed to separate these two forms. A total of 57 commercially available microalgae products based on Chlorella and Spirulina were analyzed. Results obtained showed a broad variety of the content of total vitamin B(12 )ranging from not-detectable to 445.9 mu g 100g(-1) dry matter for Chlorella samples, and be-tween 92.8 and 164.1 mu g 100g(-1) dry matter for Spirulina products. However, there was a big variation in the concentration of pseudo-vitamin B-12 within all samples analyzed. Chlorella products contained mainly physio-logically active cobalamin, while pseudo-vitamin B-12 was the prevailing form in Spirulina-labeled nutritional supplements. The importance of being able to differentiate between cobalamin and its pseudo-form in algae is not only relevant for food analysts, but also regarding consumer protection since they have to be able to rely on the correct labeling of nutritional supplements.
Authors BOKU Wien:
Mayer Helmut
Van Den Oever Sabrina

Find related publications in this database (Keywords)
Nutritional supplements
UHPLC-PDA analysis

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