University of Natural Resources and Life Sciences, Vienna (BOKU) - Research portal
Selected Publication:
Sleytr, UB; Huber, C; Ilk, N; Pum, D; Schuster, B; Egelseer, EM; .
(2007):
S-layers as a tool kit for nanobiotechnological applications.
FEMS Microbiol Lett. 2007; 267(2):131-144
- Abstract:
- Crystalline bacterial cell surface layers (S-layers) have been identified in a great number of different species of bacteria and represent an almost universal feature of archaea. Isolated native S-layer proteins and S-layer fusion proteins incorporating functional sequences self-assemble into monomolecular crystalline arrays in suspension, on a great variety of solid substrates and on various lipid structures including planar membranes and liposomes. S-layers have proven to be particularly suited as building blocks and patterning elements in a biomolecular construction kit involving all major classes of biological molecules (proteins, lipids, glycans, nucleic acids and combinations of them) enabling innovative approaches for the controlled 'bottom-up' assembly of functional supramolecular structures and devices. Here, we review the basic principles of S-layer proteins and the application potential of S-layers in nanobiotechnology and biomimetics including life and nonlife sciences.
- Authors BOKU Wien:
- Egelseer Eva Maria
- Pum Dietmar
- Schuster Bernhard
- Sleytr Uwe B.
- Find related publications in this database (using NML MeSH Indexing)
- Bacterial Proteins/chemistry*;Bacterial Proteins/genetics;Bacterial Proteins/metabolism;Biotechnology*;Liposomes/chemistry;Liposomes/metabolism;Membrane Glycoproteins/chemistry*;Membrane Glycoproteins/genetics;Membrane Glycoproteins/metabolism;Membrane Lipids/metabolism;Nanoparticles/chemistry;Nanotechnology*;Protein Conformation;Surface Properties;
- Find related publications in this database (Keywords)
- crystalline surface layers
- S-layers
- S-layer fusion proteins
- self-assembly
- bottom-up strategy
- nanobiotechnology
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