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Selected Publication:

Ezekiel, CN; Warth, B; Ogara, IM; Abia, WA; Ezekiel, VC; Atehnkeng, J; Sulyok, M; Turner, PC; Tayo, GO; Krska, R; Bandyopadhyay, R.
(2014): Mycotoxin exposure in rural residents in northern Nigeria: A pilot study using multi-urinary biomarkers
ENVIRON INT. 2014; 66: 138-145. FullText FullText_BOKU

Abstract:
A pilot, cross-sectional, correlational study was conducted in eight rural communities in northern Nigeria to investigate mycotoxin exposures in 120 volunteers (19 children, 20 adolescents and 81 adults) using a modem LC-MS/MS based multi-biomarker approach. First morning urine samples were analyzed and urinary biomarker levels correlated with mycotoxin levels in foods consumed the day before urine collection. A total of eight analytes were detected in 61/120 (50.8%) of studied urine samples, with ochratoxin A, aflatoxin M-1 and fumonisin B-1 being the most frequently occurring biomarkers of exposure. These mycotoxin biomarkers were present in samples from all age categories, suggestive of chronic (lifetime) exposures. Rough estimates of mycotoxin intake suggested some exposures were higher than the tolerable daily intake. Overall, rural consumer populations from Nasarawa were more exposed to several mixtures of mycotoxins in their diets relative to those from Kaduna as shown by food and urine biomarker data. This study has shown that mycotoxin co-exposure may be a major public health challenge in rural Nigeria; this calls for urgent intervention. (C) 2014 Elsevier Ltd. All rights reserved.
Authors BOKU Wien:
Ezekiel Chibundu Ngozi
Krska Rudolf
Sulyok Michael
Warth Benedikt
BOKU Gendermonitor:

Find related publications in this database (using NML MeSH Indexing)
Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers/urine*
Child
Child, Preschool
Chromatography, Liquid
Cross-Sectional Studies
Environmental Exposure*
Female
Food Contamination/analysis*
Humans
Infant
Male
Middle Aged
Mycotoxins/urine
Nigeria
Pilot Projects
Rural Population
Statistics as Topic
Tandem Mass Spectrometry
Young Adult

Find related publications in this database (Keywords)
Biomarker
Exposure assessment
Food safety
Human urine
Mycotoxin biomonitoring
Nigeria


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