CD Laboratory for Growth-Decoupled Protein Production in Yeast

Publications

• Engineering transcription regulation in Pichia pastoris.

  Autoren: Flores Villegas, MC; Mattanovich, D; Gasser, B Jahr: 2018

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Regulation of pseudohyphal growth and flocculation in Pichia pastoris

  Autoren: De, S; Rebnegger, C; Moser, J; Tatto, N.E; Mattanovich, D; Gasser, B; Jahr: 2018

  Conference & Workshop proceedings, paper, abstract

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• Characterization of transcription factors in Pichia pastoris

  Autoren: Flores Villegas, M; Mattanovich, D; Gasser, B Jahr: 2019

  Conference & Workshop proceedings, paper, abstract

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• Preventing morphological cell heterogeneity in the yeast Pichia pastoris (syn Komagataella phaffii): involvement of the FLO gene family.

  Autoren: De, S; Rebnegger, C; Buchetics, M; Moser, J; Tatto, N; Graf, AB; Mattanovich, D; Gasser, B. Jahr: 2021

  Conference & Workshop proceedings, paper, abstract

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• Pichia production host engineering by systemic host changes

  Autoren: Kiziak, C; Adelanto, N; Staudacher, J; Rebnegger, C; Gassser, B; Mattanovich, D Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

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• Investigating the role of oxidative stress response genes in protein secretion using a novel combinatorial Golden Gate based approach

  Autoren: Mendes Honorato, V; Staudacher, J; Prielhofer, R; Gasser, B Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in yeast

  Autoren: Staudacher, J; Rebnegger, C; Gasser, B Jahr: 2021

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• Investigating the role of oxidative stress response genes in protein secretion using a novel Golden PiCS-based approach.

  Autoren: Mendes Honorato, V; Staudacher, J; Gasser B. Jahr: 2021

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Unfolded protein response biosensors for recombinant protein expression

  Autoren: Godon, H; Puricelli, S; De, S; Adalanto, C; Kiziak, C; Gasser, B; Mattanovich, D Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

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• Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

  dc.engconfintl.org

• Maintenance energy requirement largely determines metabolic rewiring of Komagataella phaffii at glucose limited near zero growth

  Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

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• In pursuit of an orthogonal molecular switch for Komagataella phaffii

  Autoren: Malecki, P; Rebnegger, C; Gasser, B Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Maintenance energy requirements determine metabolic rewiring of Komagataella phaffii at glucose-limited near-zero growth conditions

  Autoren: Coltman, B; Rebnegger, C; Gasser, B; Zanghellini, J Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

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• Gasser, B

  Autoren: Pushing and pulling proteins into the yeast secretory pathway enhances recombinant protein secretion Jahr: 2023

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• In vivo monitoring of reactive oxygen species in the yeast Komagataella phaffii using a genetically encoded fluorescent H2O2 biosensor

  Autoren: Honorato, VM; Molin, M; Gasser, B Jahr: 2023

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

  files.spazioweb.it

• Characterising an orthogonal thiamine-responsive riboswitch for expression control in the yeast Komagataella phaffii

  Autoren: Malecki, P; Rebnegger, C; Gasser B Jahr: 2023

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

  files.spazioweb.it

• Protein production dynamics and physiological adaptation of recombinant Komagataella phaffii at near-zero growth rates

  Autoren: Rebnegger, C; Kowarz, V; Coltman, B; Mattanovich, D; Gasser, B Jahr: 2023

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• In pursuit of an orthogonal molecular switch for Komagataella phfaffii

  Autoren: Malecki, P; Rebnegger, C; Gasser, B Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• What makes Komagataella phaffii non-conventional?

  Autoren: Ata, O; Ergun, BG; Fickers, P; Heistinger, L; Mattanovich, D; Rebnegger, C; Gasser, B Jahr: 2021

  Journal articles

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• Investigating the role of oxidative stress response genes in protein secretion using a novel Golden PiCS-based approach

  Autoren: Mendes Honorato, V; Staudacher, J; Gasser B Jahr: 2021

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Going beyond the limit: Increasing global translation activity leads to increased productivity of recombinant secreted proteins in Pichia pastoris

  Autoren: Staudacher, J; Rebnegger, C; Dohnal, T; Landes, N; Mattanovich, D; Gasser, B Jahr: 2022

  Journal articles

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• Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in P. pastoris.

  Autoren: Staudacher, J; Rebnegger, C; Gasser, B Jahr: 2021

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in P. pastoris.

  Autoren: Staudacher, J; Rebnegger, C; Gasser, B Jahr: 2021

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Assessing flux rearrangements of an alternate methanol metabolism that enables efficient recombinant protein production in Pichia pastoris

  Autoren: Coltman, B; Zavec, D; Mattanovich, D; Gasser, B; Zanghellini, J Jahr: 2021

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Pichia production platform engineering by systemic changes

  Autoren: Kiziak, C; Adelantado, N; Staudacher, J; Rebnegger, C; Gasser, B; Mattanovich, D Jahr: 2022

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

  dc.engconfintl.org

• Going beyond the limit: tuning global transcription and translation activity increases recombinant protein secretion in Komagataella phaffii

  Autoren: Gasser, B; Staudacher, J; Rebnegger, C; Mattanovich, D Jahr: 2023

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Going beyond the limit: impact of increasing global translation activity on the productivity of recombinant secreted proteins in Pichia pastoris

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser, B Jahr: 2023

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Increasing global translation activity and its impact on Komagataella phaffii

  Autoren: Staudacher, J; Rebnegger, C; Mattanovich, D; Gasser B Jahr: 2023

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

  files.spazioweb.it

• Systematic sequence engineering enhances the induction strength of the glucose-regulated GTH1 promoter of Komagataella phaffii.

  Autoren: Flores-Villegas, M; Rebnegger, C; Kowarz, V; Prielhofer, R; Mattanovich, D; Gasser, B; Jahr: 2023

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• Slow Growth Rate triggered transition to a pseudohyphal lifestyle of the protein production host Pichia pastoris

  Autoren: De, S; Buchetics, M; Rebnegger, C; Mattanovich, D; Gasser, B Jahr: 2019

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• Dissection of growth-rate- and cell-cycle-dependent gene regulation in P-pastoris

  Autoren: Rebnegger, C; Burgard, J; Graf, AB; Maurer, M; Gasser, B; Mattanovich, D Jahr: 2018

  Journal articles

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• Protein production dynamics and physiological adaptiation of recombinant Pichia pastoris at near-zero growth rates

  Autoren: Rebnegger, C; Kowarz, V; Mattanovich, D; Gasser, B Jahr: 2019

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication:

• XS™ Pichia 2.0: closing the gap between bacterial and mammalian systems for the production of recombinant proteins

  Autoren: Adelantado, N; Claes, K; Reichinger, M; Wagner, N; Prielhofer, R; Gasser, B; Mattanovich, D; Kiziak, Ch Jahr: 2019

  Conference & Workshop proceedings, paper, abstract

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• Impact of puromycin on different Pichia pastoris strains

  Autoren: Staudacher, J: Gasser, B; Jahr: 2018

  Conference & Workshop proceedings, paper, abstract

  external links and characteristics of the publication: