Flow-structure interaction in pulsatile flow of non-Newtonian fluids
Abstract
The proposed research addresses a novel and highly relevant question in biomedical research today: how does the interaction of blood flow with flexible walls affect the transition to turbulence the human aorta? We expect our project to provide the foundation for a new understanding of the origin of disordered blood flow in realistic cardiovascular flows and in particular how the transition to turbulence depends on characteristics of wall material and non-Newtonian fluid properties. This will be relevant for understanding the relation between blood flow and vascular diseases as it will improve our ability to predict blood transport efficiency with decreasing aortic compliance in atherosclerosis. Crucially, this ambitious effort leverages the unique groundwork done in the first funding phase, where we set up a novel experimental setup for the study of flow-structure interaction in pulsatile flow and established novel methodologies to advance the understanding of flow-structure interactions in flexible pipes and aorta replicas. In the second funding phase we will now include fluid rheology and aim to elucidate the impact of flexible walls on transition to turbulence in non-Newtonian fluids. This will be achieved by looking at the stability of pulsatile flow in elastic pipes and flexible aortas and we will consider shear thinning fluids and viscoelastic polymer solutions. We therefore address core areas of the Program, namely the understanding of flow regimes in pulsating systems with complex geometries and we provide a strong link to medically relevant applications.
Publikationen
Project staff
Markus Holzner
Ass.Prof. Dr. Markus Holzner MSc.
markus.holzner@boku.ac.at
Tel: +43 1 47654-81945
Project Leader
01.11.2023 - 31.10.2026