PIN2 Ubiquitination and Degradation
Abstract
In this project, we intend to study the consequences of plant plasma membrane protein ubiquitination in general and, by using PIN2 as a model protein, its regulatory implications for auxin distribution and growth responses in particular. Localization studies together with targeted mutagenesis of PIN2 should reveal cis-acting determinants that control PIN2 ubiquitination and consequences of ubiquitination on PIN2 distribution and degradation. Moreover, it is planned to characterize a number of candidate loci that appear to control PIN2 protein levels and expression pattern in trans. Overall, suggested work should provide us with a framework of regulatory events that integrate intrinsic and external signals and the control of developmental processes via regulation of PIN protein levels.
Publications
Differential degradation of PIN2 auxin efflux carrier by retromer-dependent vacuolar targeting.
Autoren: Kleine-Vehn, J; Leitner, J; Zwiewka, M; Sauer, M; Abas, L; Luschnig, C; Friml, J Jahr: 2008
Journal articles
Project staff
Christian Luschnig
Assoc. Prof. Dr. Christian Luschnig
christian.luschnig@boku.ac.at
Tel: +43 1 47654-94230
Project Leader
01.02.2007 - 31.01.2012
Melinda Frances Anna Abas
Dr. Melinda Frances Anna Abas
melinda.abas@boku.ac.at
Tel: +43 1 47654-94025
Project Staff
01.02.2007 - 31.01.2012