Lukas Mach

Univ.Prof. Dipl.-Ing.Dr.nat.techn. Lukas Mach
Institute of Plant Biotechnology and Cell Biology
Standort Muthgasse 18, 1190 Wien
Email lukas.mach@boku.ac.at
Tel: +43 1 47654-94065, 94360

ORCID: 0000-0001-9013-5408

Meine Lehrveranstaltungen

Forschungsschwerpunkt

Biosynthesis and intracellular trafficking of secretory and lysosomal/vacuolar proteins, glycosylation and other post-translational protein modifications as determinants of protein structure and function, catalytic properties and physiological functions of proteases and glycosylation enzymes, proteolysis and its pathological and biotechnological relevance, recombinant expression of biotherapeutics in plants and insect cells.

glycobiology proteases cell biology

Laufbahn

2018 Full Professor of Cell Biology, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna
2010 - 2014 Head of Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna
2004 - 2018 Associate Professor at Institute of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna
1999 - 2004 Assistant Professor at Center of Applied Genetics, University of Natural Resources and Life Sciences, Vienna (BOKU)
1995 - 1999 Assistant Professor ("Lecturer"), Dept. of Biochemistry, University of Western Australia, Nedlands, Australia
1994 - 1995 Scientist, Division of Immunological Research, IMMUNO AG, Vienna
1989 - 1994 Doctoral studies (McGill University, Montreal, Canada; University of Natural Resources and Life Sciences, Vienna)

Projekte

Es wurden 0 Projekte gefunden.

Publikationen

Wissentransfer in die Gesellschaft

Medienbeiträge

Vorträge

Es wurden 23 gefunden.

: 2022 - Factors defining the proteolytic susceptibility of monoclonal antibodies in the tobacco apoplast

Art: Vortrag - Keynote Speaker (eingeladener Vortrag)

Autoren: Mach, L

: 5th Conference on Plant Proteases

: 06.09.2022 - 08.09.2022 | : Ljubljana, Slovenia
: 2015 - Unable to express one of leptospiral genes of leucine-rich repeat protein in Lactobacillus plantarum

Art: Poster - Ausgewählte Präsentation

Autoren: Suphatpahirapol, C; Nguyen, TH; Mach, L; Nitipane, S; Wajjwalku, W; Keawsompong, S; Haltrich, D; Prapong, S

: Eigth Asian Conference for Lactic Acid Bacteria ACLAB 2015

: 08.07.2015 - 10.07.2015 | : Bangkok, Thailand
: 2014 - Proteolysis of Anti-HIV Antibodies Manufactured in Nicotiana Benthamiana: Identification and Characterization of Antibody-Degrading Papain-Like Cysteine Proteinases

Art: Vortrag - Keynote Speaker (eingeladener Vortrag)

Autoren: Niemer, M; Mehofer, U; Verdianz, M; Porodko, A; Schähs, P; Kracher, D; van der Hoorn, R; Lenarcic, B; Novinec, M; Mach, L

: 14th International Symposium on Proteinases, Inhibitors and Biological Control 2014

: 06.09.2014 - 10.09.2014 | : Portoroz, Slovenia
: 2013 - The role of the mannose 6-phosphate/insulin-like growth factor II receptor and its ligands in cancer cell invasion

Art: Vortrag - Keynote Speaker (eingeladener Vortrag)

Autoren: Mach, L

: Colloquia in Chemical Sciences, University of Ljubljana

: 17.04.2013 | : Ljubljana, Slovenia
: 2012 - Degradation of recombinant proteins by plant cysteine proteinases

Art: Vortrag - Keynote Speaker (eingeladener Vortrag)

Autoren: Niemer, M; Mehofer, U; Verdianz, M; Schaller, A; van der Hoorn, R; Mach, L

: FA0804 COST Action Molecular farming 2012 -Plants as a production platform for high value proteins

: 16.02.2012 - 17.02.2012 | : Vienna, Austria
: 2012 - Human cathepsin O: glycosylation, processing and cellular activity

Art: Vortrag - Keynote Speaker (eingeladener Vortrag)

Autoren: Aufy, M; Porodko, A; Stadlmann, J; Gruber, C; Mach, L

: 13th International Symposium on Proteinases, Inhibitors and Biological Control 2012

: 22.09.2012 - 26.09.2012 | : Portoroz, Slovenia
: 2011 - Degradation of recombinant monoclonal antibodies by plant cysteine proteinases

Art: Vortrag - Ausgewählte Präsentation

Autoren: Mach, L.

: 1st International Plant Protease Conference 2011

: 10.04.2011 - 14.04.2011 | : Hemavan, Sweden
: 2011 - The human lysosomal cysteine protease cathepsin O is N- and O-glycosylated

Art: Poster - Ausgewählte Präsentation

Autoren: Aufy, M., Porodko, A., Stadlmann, J., Mach, L.

: 21st International Symposium on Glycoconjugates GLYCO 21, 2011

: 21.08.2011 - 26.08.2011 | : Vienna, Austria | : The International Glycoconjugate Organisation | : Universität für Bodenkultur Wien, Universität Wien, BMWF
: 2011 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

Art: Vortrag - Ausgewählte Präsentation

Autoren: Aufy, M., Nimmerfall, E., Mach, L.

: 28th Winter School on Proteinases and Their Inhibitors 2011

: 23.02.2011 - 27.02.2011 | : Tiers, Italy
: 2011 - The role of the mannose 6-phosphate/IGF-II receptor and it's diverse ligands in cancer cell invasion

Art: Vortrag - Ausgewählte Präsentation

Autoren: Mach, L.

: ICA Symposium 2011

: 01.07.2011 - 02.07.2011 | : Salzburg, Austria
: 2011 - The two N-glycans of murine Cellular Repressor of E1A-stimulated Genes (CREG) are both engaged in lysosomal sorting of the protein

Art: Poster - Ausgewählte Präsentation

Autoren: Schähs, P., Schönbacher, A., Steinschauer, V., Porodko, A., Stadlmann, J., Mach, L.

: 21st International Symposium on Glycoconjugates GLYCO 21, 2011

: 21.08.2011 - 26.08.2011 | : Vienna, Austria | : The International Glycoconjugate Organisation | : Universität für Bodenkultur Wien, Universität Wien, BMWF
: 2011 - Antonio Baici and the mysteries of tumour cathepsin B

Art: Vortrag - Ausgewählte Präsentation

Autoren: Mach, L.

: Symposium in the honour of Antonio Baici and Heinz Gehring, University of Zürich 2011

: 15.04.2011 | : Zürich, Switzerland
: 2010 - Characterization of Drosophila melanogaster cellular repressor of E1A-stimulated genes (CREG)

Art: Poster - Ausgewählte Präsentation

Autoren: Schähs, P., Mach, L.

: 2nd ÖGMBT Annual Meeting 2010

: 27.09.2010 - 29.09.2010 | : Vienna, Austria | : ÖGMBT (Österreichische Gesellschaft für Molekulare Biowissenschaften und Biotechnologie)
: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

Art: Vortrag - Ausgewählte Präsentation

Autoren: Aufy, M., Nimmerfall, E., Mach, L.

: 12th Symposium on Proteases, Inhibitors and Biological Control 2010

: 25.09.2010 - 29.09.2010 | : Portoroz, Slovenia
: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

Art: Poster - Ausgewählte Präsentation

Autoren: M. Aufy, E. Nimmerfall, L.Mach

: 2nd ÖGMBT Annual Meeting 2010

: 27.09.2010 - 29.09.2010 | : Vienna, Austria | : ÖGMBT (Österreichische Gesellschaft für Molekulare Biowissenschaften und Biotechnologie)
: 2009 - Consistent β1,4-galactosylation of monoclonal antibodies produced in plants.

Art: Poster - Ausgewählte Präsentation

Autoren: Castilho, A; Strasser, R; Stadlmann, J; Kunert, R; Gattinger, P; Altmann, F; Mach, L; Steinkellner, H

: 15th European Carbohydrate Symposium 2009

: 19.07.2009 - 24.07.2009 | : Vienna, Austria | : BOKU Wien | : BOKU, Universität Wien
: 2009 - Cloning, expression and purification of human recombinant lactoperoxidase

Art: Vortrag - Ausgewählte Präsentation

Autoren: Stampler, J., Furtmüller, P.G., Soudi, M., Mach, L., Obinger, C.

: 6th International Human Peroxidase Meeting 2009

: 19.04.2009 - 22.04.2009 | : Chapel Hill, NC, USA
: 2009 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of Arabidopsis N-glycans with Lewis A epitopes.

Art: Vortrag - Ausgewählte Präsentation

Autoren: Strasser, R., Vavra, U., Schoberer, J., Svoboda, B., Glössl, J., Leonard, R., Altmann, F., Steinkellner, H., Mach, L.

: 15th European Carbohydrate Symposium 2009

: 19.07.2009 - 24.07.2009 | : Vienna, Austria | : BOKU Wien | : BOKU, Universität Wien
: 2009 - Role of β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans in plants

Art: Vortrag - Ausgewählte Präsentation

Autoren: Glössl, J., Liebminger, E., Schoberer, J., Svoboda, B., Altmann, F., Steinkellner, H., Mach, L., Strasser, R.

: GLYCOBIOLOGY 2009

: 12.11.2009 - 15.11.2009 | : San Diego, CA, USA
: 2009 - Role of Arabidopsis β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans.

Art: Poster - Ausgewählte Präsentation

Autoren: Liebminger, E., Schoberer, J., Svoboda, B., Glössl, J., Altmann, F., Steinkellner, H., Mach, L., Strasser, R.

: 15th European Carbohydrate Symposium 2009

: 19.07.2009 - 24.07.2009 | : Vienna, Austria | : BOKU Wien | : BOKU, Universität Wien
: 2009 - Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously β1,4-galactosylated human-type N-glycans.

Art: Vortrag - Ausgewählte Präsentation

Autoren: Glössl, J., Strasser, R., Castilho, A., Kunert, R., Altmann, F., Mach, L., Steinkellner, H.

: GLYCOBIOLOGY 2009

: 12.11.2009 - 15.11.2009 | : San Diego, CA, USA
: 2008 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of plant N-glycans with Lewis a epitopes

Art: Poster - Ausgewählte Präsentation

Autoren: Strasser, R., Vavra, U., Schoberer, J., Svoboda, B., Glössl, J., Léonard, R., Stadlmann, J., Altmann, F., Steinkellner, H., Mach, L.

: 6th International Conference on Glycosyltransferases GlycoT 2008

: 17.05.2008 - 20.05.2008 | : Atlanta, GA, USA
: 2008 - Role of Arabidopsis beta-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans

Art: Poster - Ausgewählte Präsentation

Autoren: Liebminger, E., Schoberer, J., Svoboda, B., Glössl, J., Altmann, F., Steinkellner, H., Mach, L., Strasser, R.

: 26th Congress of the Federation of European Societies of Plant Biology FESPB 2008 tohether with 11th annual international meeting for experimental moss research and 8th International Peroxidase Symposium, Peroxidase 2008

: 17.08.2008 - 22.08.2008 | : Tampere, Finland

Lukas Mach

Forschungsschwerpunkt

Laufbahn

Projekte

Publikationen

Wissentransfer in die Gesellschaft

Medienbeiträge

Vorträge

: 2022 - Factors defining the proteolytic susceptibility of monoclonal antibodies in the tobacco apoplast

: 2015 - Unable to express one of leptospiral genes of leucine-rich repeat protein in Lactobacillus plantarum

: 2014 - Proteolysis of Anti-HIV Antibodies Manufactured in Nicotiana Benthamiana: Identification and Characterization of Antibody-Degrading Papain-Like Cysteine Proteinases

: 2013 - The role of the mannose 6-phosphate/insulin-like growth factor II receptor and its ligands in cancer cell invasion

: 2012 - Degradation of recombinant proteins by plant cysteine proteinases

: 2012 - Human cathepsin O: glycosylation, processing and cellular activity

: 2011 - Degradation of recombinant monoclonal antibodies by plant cysteine proteinases

: 2011 - The human lysosomal cysteine protease cathepsin O is N- and O-glycosylated

: 2011 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

: 2011 - The role of the mannose 6-phosphate/IGF-II receptor and it's diverse ligands in cancer cell invasion

: 2011 - The two N-glycans of murine Cellular Repressor of E1A-stimulated Genes (CREG) are both engaged in lysosomal sorting of the protein

: 2011 - Antonio Baici and the mysteries of tumour cathepsin B

: 2010 - Characterization of Drosophila melanogaster cellular repressor of E1A-stimulated genes (CREG)

: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

: 2009 - Consistent β1,4-galactosylation of monoclonal antibodies produced in plants.

: 2009 - Cloning, expression and purification of human recombinant lactoperoxidase

: 2009 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of Arabidopsis N-glycans with Lewis A epitopes.

: 2009 - Role of β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans in plants

: 2009 - Role of Arabidopsis β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans.

: 2009 - Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously β1,4-galactosylated human-type N-glycans.

: 2008 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of plant N-glycans with Lewis a epitopes

: 2008 - Role of Arabidopsis beta-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans

Betreute Hochschulschriften

Community Services

Lukas Mach

Forschungsschwerpunkt

Laufbahn

Projekte

Publikationen

Wissentransfer in die Gesellschaft

Medienbeiträge

Vorträge

: 2022 - Factors defining the proteolytic susceptibility of monoclonal antibodies in the tobacco apoplast

: 2015 - Unable to express one of leptospiral genes of leucine-rich repeat protein in Lactobacillus plantarum

: 2014 - Proteolysis of Anti-HIV Antibodies Manufactured in Nicotiana Benthamiana: Identification and Characterization of Antibody-Degrading Papain-Like Cysteine Proteinases

: 2013 - The role of the mannose 6-phosphate/insulin-like growth factor II receptor and its ligands in cancer cell invasion

: 2012 - Degradation of recombinant proteins by plant cysteine proteinases

: 2012 - Human cathepsin O: glycosylation, processing and cellular activity

: 2011 - Degradation of recombinant monoclonal antibodies by plant cysteine proteinases

: 2011 - The human lysosomal cysteine protease cathepsin O is N- and O-glycosylated

: 2011 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

: 2011 - The role of the mannose 6-phosphate/IGF-II receptor and it's diverse ligands in cancer cell invasion

: 2011 - The two N-glycans of murine Cellular Repressor of E1A-stimulated Genes (CREG) are both engaged in lysosomal sorting of the protein

: 2011 - Antonio Baici and the mysteries of tumour cathepsin B

: 2010 - Characterization of Drosophila melanogaster cellular repressor of E1A-stimulated genes (CREG)

: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

: 2010 - Biosynthesis, intracellular transport and subcellular localization of human cathepsin O

: 2009 - Consistent β1,4-galactosylation of monoclonal antibodies produced in plants.

: 2009 - Cloning, expression and purification of human recombinant lactoperoxidase

: 2009 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of Arabidopsis N-glycans with Lewis A epitopes.

: 2009 - Role of &#946;-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans in plants

: 2009 - Role of Arabidopsis &#946;-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans.

: 2009 - Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously &#946;1,4-galactosylated human-type N-glycans.

: 2008 - Characterization of the beta1,3-galactosyltransferase indispensable for the modification of plant N-glycans with Lewis a epitopes

: 2008 - Role of Arabidopsis beta-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans

Betreute Hochschulschriften

Community Services

: 2009 - Role of β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans in plants

: 2009 - Role of Arabidopsis β-N-acetylhexosaminidases in the formation of paucimannosidic N-glycans.

: 2009 - Glyco-engineering in plants: production of monoclonal antibodies containing homogeneously β1,4-galactosylated human-type N-glycans.